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Inspiring Hope on Rare Disease Day 2025: Exploring DMD and Next-Generation PMO/PPMO Therapies with WuXi TIDES
Every year on Rare Disease Day, patients, families, and researchers join forces to draw attention to the unmet needs of those living with rare diseases. In honor of Rare Disease
A Comparison of 11-Monomer PNA synthesis
A Comparison of 11-Monomer PNA synthesis: Literature Protocol vs. Our Enhanced Method Our Advantages: No need of Tenta Gel resin High crude purity High yield Fast reaction time Download Full
The Role of Benchmarking Critical Impurity Control in Therapeutic Oligonucleotide Phosphoramidites
The growing need for oligonucleotide therapeutics aimed at larger patient populations has driven the demand for high-quality nucleoside phosphoramidite which are building blocks for oligonucleotide therapeutics. The global oligonucleotide therapeutics
Mastering and Accelerating sgRNA Synthesis: Unveiling Success Strategies
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Case Study: From Discovery to Phase I, Rapid Delivery of a Complex Peptide Conjugate in 10 Months
Abstract: In the highly competitive peptide market, speed is critical for the success of novel peptide therapeutic development. This case study shows how WuXi TIDES scientists accelerate the development of
Case Study: Fast-Track to Phase I: Two siRNA IND CMC Packages Completed in 14 Months
Abstract: A biotech company engaged WuXi TIDES to develop a siRNA-GalNAc drug candidate for cardiovascular disease. The original synthesis process for this 23-mer siRNA resulted in a yield of 13%
